We are happy to announce another OCBE biostatistics seminar, next Thursday, June 3rd, at 13:15 (NOTE: EARLIER TIME THAN USUAL).

Céline Cunen, Postdoc, and Nils Lid Hjort, Professor, Department of Mathematics, University of Oslo, will present
“Combining Information Across Diverse Sources: The II‐CC‐FF Paradigm”.

Zoom link: https://uio.zoom.us/j/64312662291?pwd=VEl6ZUh6VVA2dDVHS1ZCUU03OVExUT09

Abstract: We introduce and develop a general paradigm for combining information across diverse data sources. In broadterms, suppose ϕ is a parameter of interest, built up via components ψ1,…,ψk from data sources 1,…,k. The proposed scheme has three steps. First, the independent inspection (II) step amounts to investigating each separate data source, translating statistical information to a confidence distribution (CD) Cj(ψj) for the relevant focus parameter ψj associated with data source j. Second, confidence conversion (CC) techniques are used to translate the CDs to confidence log-likelihood functions. Finally, the focused fusion (FF) step uses relevant and context-driven techniques to construct a confidence distribution for the primary focus parameter ϕ=ϕ(ψ1,…,ψk), acting on the combined confidence log-likelihood. In traditional setups, the II-CC-FF strategy amounts to versions of meta-analysis, and turns out to be competitive against state-of-the-art methods. Its potential lies in applications to harder problems, however. Illustrations are presented, related to actual applications.

The talk is based on their recent publication in SJOS: https://onlinelibrary.wiley.com/doi/epdf/10.1111/sjos.12530

See also: https://www.med.uio.no/imb/english/research/centres/ocbe/events/biostat-seminar/

Welcome!
Best wishes,
Manuela Zucknick and Jon Michael Gran