We are pleased to announce that Dr. Renée Beekman will be the guest speaker of our upcoming Sven Furberg Seminar in Bioinformatics and Statistical Genomics on Thursday April 28th at 14:30 at the Lille Auditorium, Kristen Nygaard's building (see info at https://www.mn.uio.no/sbi/english/furberg-seminars/dr.-renee-beekman.html)
If you want to meet Dr. Beekman on Thursday April 28th in Forskningsparken, book a time slot at https://doodle.com/meeting/participate/id/b82XKWLe. Please book an empty slot for maximum 1 hour and send an email to anthony.mathelier@ncmm.uio.no to confirm the time.
Dr. Renée Beekman, Group Leader at the Centre for Genomic Regulation, Barcelona, Spain, will present her lecture "Understanding early lymphoma formation from a single-cell epigenomics and 3D chromatin perspective."
Abstract
Translocations and epigenetic changes are frequently found in cancer. However, how the epigenetic landscape evolves during early tumor formation and how translocations play a role in this process remain largely unexplored. Neither is it know if oncogenic epigenetic events occur in healthy individuals, which could provide seeds for positive selection and tumor formation. In this talk, I will present (i) a new single-cell DNA methylation method that we have developed in the lab to characterise the DNA methylation landscape in healthy B cells as well as (ii) a study of the global effects of translocations on 3D chromatin organization, using mantle cell lymphoma (MCL) as a model.
More information at https://www.mn.uio.no/sbi/english/furberg-seminars/dr.-renee-beekman.html.
Looking forward to seeing you all at the seminar.
Best
Anthony & Manuela