Dear all,
The next OCBE biostatistics seminar will be held on Thursday, April 27th, at 14:30-15:30 in Auditorium 13 (Domus Medica, Oslo). 

William Denault, Researcher, Oslo Centre for Biostatistics and Epidemiology, Oslo University Hospital, will present about

Introduction to the Sum of Single Effects (SuSiE) model and its recent extensions

Abstract: In this presentation, we present in detail the seminal work of Wang et al. "Sum of Single Effects" (SuSiE) model (JRSSB 2021) — introducing a simple new approach to variable selection in linear regression, with a particular focus on quantifying uncertainty in which variables should be selected. We also introduce a corresponding new fitting procedure — Iterative Bayesian Stepwise Selection (IBSS) — which is a Bayesian analogue of stepwise selection methods. IBSS shares the computational simplicity and speed of traditional stepwise methods, but instead of selecting a single variable at each step, IBSS computes a distribution on variables that captures uncertainty in which variable to select. We provide a formal justification of this intuitive algorithm by showing that it optimizes a variational approximation to the posterior distribution under the SuSiE model. Finally, we will discuss extension of the SuSiE model to summary statistics regression and functional phenotypes.

The OCBE biostatistics seminar series is organized by the Oslo Centre for Biostatistics and Epidemiology and is an arena for presenting new interesting work in biostatistics, both on the methodological and applied side, from researchers in Oslo, from Norway and abroad.

See also: https://www.med.uio.no/imb/english/research/centres/ocbe/events/biostat-seminar/
for updates or for subscribing to the events. If you'd like to be added in the "biostat-ext" mailing list, just let us know.

Other upcoming seminars this semester:

May 25th, 2023:  Francesco Stingo, University of Florence, Italy
June 15th, 2023: Susanne Strohmaier, Medical University of Vienna, Austria

Welcome!
Best wishes,
Jon Michael Gran, Valeria Vitelli and Manuela Zucknick